Yellow nail syndrome

Yellow nail syndrome is a triad of: 

• Dystrophic, slow growing yellow nails 
• Lymphoedema 
• Respiratory manifestations (pleural effusion/bronchiectasis/recurrent lung infections)

2 of the 3 are required for diagnosis

Conditions associated with yellow nail syndrome include: 

• Rheumatoid arthritis 
• TB 
• Malignancy 
• Diabetes
• Thyroid dysfunction 

References:

Hershko, A. et al. Yellow nail syndrome. Postgrad Med J. 1997; 73(862): 466-468. 

Maldonado, F. et al. Yellow nail syndrome: analysis of 41 consecutive patients. Chest. 2008; 134(2): 375-381.

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