Pick’s disease is the eponym for frontotemporal dementia.
Characteristics of frontotemporal dementia include:
- Insidious onset and gradual progression
- Decline in social skills and loss of inhibitions
- Emotional blunting
- Loss of insight
- Loss of language skills
- Onset before age 65
Whereas in other forms of dementia memory is impaired, in frontotemporal dementia memory remains intact.
The histological feature of frontotemporal dementia is tau-positive neuronal cytoplasmic inclusions.
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