Henoch-Schonlein Purpura (HSP) is an IgA mediated small-vessel vasculitis.
The classical features are:
- Purpuric rash on extensor surfaces of legs and buttocks
- Abdominal pain
- Arthralgia
- Haematuria often with proteinuria
Other possible features include
- Renal involvement
- Glomerulonephritis
- Nephrotic syndrome
- Abdominal complications
- Bloody stools
- Intussuception in children
- Bowel ischaemia
It often follows an upper respiratory tract infection
HSP can affect all ages but is commest in children under 10.
Males>females, 2:1
Treatment:
Symptomatic
? steroids for severe HSP nephritis
References:
