Acute promyelocytic leukaemia

Acute promyelocytic leukaemia is the M3 subtype of AML

Features include:
  • translocation t(15;17) that produces the PML-RARα gene
  • bundles of auer rods (=faggots

It predisposes to DIC, but as long as this is treated its prognosis is good with treatment with all trans retinoic acid or arsenic trioxide.

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Secret collector of interesting anonymised ECGs. Fan of the Bath Photomarathon. Lover of cream teas. [Sarah Hudson] (Your Picture)