Lymphadenopathy

Causes of generalized lymphadenopathy

• Neoplastic 
• Lymphoma
• leukaemia
• Infective 
• EBV 
• CMV
• HIV
• TB
• Toxoplasmosis
• Medications 
• Allopurinol 
• Atenolol
• Penicillin 
• Phenytoin
• Quinidine 
• Rheumatological
• RA
• SLE 
• Sarcoidosis
• Storage diseases 
• Gaucher’s disease 
• Fabry’s disease

Causes of local lymphadenopathy

• Local infection
• Neoplasia

Small print gems: 

Virchow's node - left supraclavicular node associated with intraabdominal cancer

Sister Mary Joseph node - umbilical node associated with intraabdominal cancer

References

Bazemore, A. and Smucker, D. Lymphadenopathy and malignancy. Am Fam Physician. 2002; 66(11): 2103-2110. 

Ferrer, R. Lympadenopathy: differential diagnosis and evaluation. Am Fam Physician. 1998; 58(6): 1313-1320. 

Karpf, M. Lymphadenopathy. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 149.