HELLP syndrome

HELLP syndrome is a complication of pregnancy, often regarded as a variation or progression of pre-eclampsia.

HELLP syndrome comprises of:

• Haemolysis 
• Elevated Liver enzymes 
• Low platelets 

It complicates 10-20% of cases of severe pre-eclampsia 

HELLP occurs pre-partum in 70% of cases and post-partum in around 30%, usually within 48 hours of delivery 

Presentation tends to be

• Epigastric pain
• Headache 
• Nausea and vomiting 

Treatment is delivery of baby. 

Mortality can be as high as 25%. 

References

Haram, K., Svendsen, E. and Abildgaard, U. The HELLP syndrome: clinical issues and management. A Review. BMC Pregnancy Childbirth. 2009; 9: 8.

Padden, M. HELLP syndrome: recognition and perinatal management. Am Fam Physician. 1999; 60(3): 829-836.