Goodpasture’s syndrome is a rare autoimmune disease characterised by:
- Pulmonary haemorrhage
- Rapidly progressive glomerulonephritis and renal failure
The cause is anti-GBM antibodies acting against type IV collagen
Pulmonary haemorrhage occurs most commonly in patients who are smokers, or are exposed to paint of gasoline fumes
Treatment:
- Prednisolone
- Cyclophosphamide
- Plasma exchange
References:
