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Gilbert’s syndrome

Gilbert’s syndrome is a cause of hereditary hyperbilirubinaemia.  It is inherited in an autosomal recessive fashion.

It results in a predominantly unconjugated hyperbilirubinaemia due to decreased levels of glucoronyltransferase. 

LFTs are normal except for mildly elevated bilirubin, which tends to only be clinically apparent when individuals are fasting, unwell, dehydrated or tired. 

5-10% of the population are affected. It is benign and no specific treatment is required. 


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Abdelghafour

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Secret collector of interesting anonymised ECGs. Fan of the Bath Photomarathon. Lover of cream teas. [Sarah Hudson] (Your Picture)