Gilbert’s syndrome

Gilbert’s syndrome is a cause of hereditary hyperbilirubinaemia.  It is inherited in an autosomal recessive fashion.

It results in a predominantly unconjugated hyperbilirubinaemia due to decreased levels of glucoronyltransferase. 

LFTs are normal except for mildly elevated bilirubin, which tends to only be clinically apparent when individuals are fasting, unwell, dehydrated or tired. 

5-10% of the population are affected. It is benign and no specific treatment is required. 

author profile image

Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book.

Secret collector of interesting anonymised ECGs. Fan of the Bath Photomarathon. Lover of cream teas. [Sarah Hudson] (Your Picture)