Cardiac tamponade occurs when fluid accumulates in the pericardium and exerts a pressure that exceeds intracardiac pressures, leading to impaired cardiac output. 
Normally the pericardial space contains 15-50mls of fluid.  If fluid accumulates slowly it can accommodate up to 2l without causing tamponade; however, if it accumulates rapidly 150-200mls can result in tamponade. 
Possible causes of tamponade are any cause of a pericardial effusion. 
The classic clinical triad is Becks (present in 10 to 40% of cases): 
- falling BP
 - rising JVP
 - muffled heart sounds
 
Other clinical signs and symptoms include:
- Shortness of breath
 - Chest pain
 - Palpitations
 - Tachycardia
 - Pulsus paradoxus = increased fall in BP during inspiration >10mmHg - present in 98%
 - Raised JVP with decreased y descent
 - Kussmaul’s sign = rising JVP on inspiration (more common in constrictive pericarditis than tamponade)
 - Ewart’s sign = area of dullness and bronchial breathing below left scapular due to pericardial collection
 
Investigations 
- ECG
 - Low voltages complexes
 - Electrical alternans (present in 10 to 20%)
 - CXR
 - 'flask-like’ cardiac shadow if slow accumulation\
 - may be normal if rapid
 - Echo
 - RA+/-RV collapse during diastole
 
Treatment: 
Pericardiocentesis or cardiothoracic surgery 
References: 
Bandinelli, G., Lagi, A. and Modesti, P. Pulsus paradoxus: an underused tool. Intern Emerg Med. 2007; 2(1): 33-35.
European Society of Cardiology. Guidelines on the Diagnosis and Mnaagement of Pericardial Diseases. Available at http://www.escardio.org/guidelines-surveys/esc-guidelines/Pages/pericardial-diseases.aspx
European Society of Cardiology. Guidelines on the Diagnosis and Mnaagement of Pericardial Diseases. Available at http://www.escardio.org/guidelines-surveys/esc-guidelines/Pages/pericardial-diseases.aspx
