Renal papillary necrosis

Renal papillary necrosis is selective tissue death of the renal papilla causing a nephropathy

Presentation may be with loin pain and haematuria. It can cause both acute and chronic renal failure

  • Most common: 
    • Analgesic overuse
    • Urinary tract obstruction 
    • Diabetes 
    • Sickle cell 
  • Other: 

Pyelonephritis is often listed as a cause but this is controversial – it is difficult to determine if it is in fact a cause or an effect. 

Investigation is with IVU or CT. 
Urine may show a sterile pyuria.

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